mutations on protein-DNA and protein-RNA interactions

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wyomdnavaccine

Optimising glyphosate tolerance in rapeseed (Brassica napus L.) by CRISPR/Cas9-based geminiviral donor DNA replicon system with Csy4-based single-guide RNA processing Rapeseed (Brassica napus L.) is a crucial oil crop worldwide, and efficient weed management can shield its yields and high quality. Farmers can profit from tolerant cultivars when utilizing herbicides, corresponding to glyphosate. Amino acid substitutions in enolpyruvylshikimate-3-phosphate synthase […]

Opposite roles of transcription elongation factors

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wyomdnavaccine

In Silico screening of circulating tumor DNA, circulating microRNAs, and lengthy non-coding RNAs as diagnostic molecular biomarkers in ovarian most cancers: A complete meta-analysis Background: Ovarian most cancers (OC) is a number one explanation for dying in gynecological malignancies worldwide. Multitudinous research have urged the potential of circulating tumor DNA (ctDNA), circulating microRNAs (miRNAs), and lengthy non-coding RNAs (lncRNAs) […]

CCG trinucleotide repeat expansion rationalizes the RNA misprocessing in FXTAS

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wyomdnavaccine

Secondary structural selection of DNA and RNA related to CGG/CCG trinucleotide repeat growth rationalizes the RNA misprocessing in FXTAS   CGG tandem repeat growth within the 5′-untranslated area of the delicate X psychological retardation-1 (FMR1) gene results in uncommon nucleic acid conformations, therefore inflicting genetic instabilities. We present that the variety of G…G (in CGG repeat) or C…C (in CCG repeat) […]